توسط در 1395/12/7
توسعه پرشتاب فناوریه ای نوین زیستی و مولکولی و کشف فرایند های زیستی در حوزه بیماری ها در حال گشودن دریچه های جدیدی برای توسعه سامت در جامعه است. شناخت ما از مکانیسم های سلولی و مولکولی و علل و ریشه بیماری ها و آسیب ها، دانش پزشکی را به سمت و سویی صحیح آن سوق می دهد. پایان پروژه ژنوم انسان در سال 2003 آغازی برای شناخت دقیق تر اندازه ژنوم انسان، تعداد ژن ها و پروتئین ها و نقش آنها در عملکردهای سلولی و بیماری ها بود.
The use of cytokines as adjuvants has been shown to be a promising approach for enhancing DNA vaccine induced-immune responses. In this report, we investigate the administration of cytokines to modulate both humoral and cell-mediated immune responses elicited by an HCV-core plasmid DNA vaccine in Balb/c mice.
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1Faculty of Sciences, Tarbiat Modarres University, PO Box 14115-111, Tehran, Iran 2Institute of Biochemistry and Biophysics, University of Tehran, PO Box 13145-1384, Tehran, Iran 3Institute of Medicinal and Pharmaceutical Chemistry, University of Vienna, Vienna, Austria 4Research Canter for Molecular Biology, Baqyetallah University of Medical Sciences, PO Box 19945-581, Iran
To provide a new reasonable measure for distinguishing between coding and non-coding regions of DNA sequences based on its fractal nature and self-similarity. Study design: After conducting background studies on the fractal structure of DNA sequences, the application of Detrended Fluctuation Analysis for identifying coding and non-coding regions in those sequences was investigated.
Several factors have been suggested to account for differences in the virulence of Helicobacter pylori infections in various populations. Evidence suggests the existence of different strains of H. pylori with different degrees of virulence.
In this study, directly observed short course therapy (DOTS) was implemented to control tuberculosis in a camp in Iran. First, one study had been conducted in 1996 (before DOTS implementation) as active case finding then DOTS have been implemented in 1997.
One of the largest genomes belongs to a very small creature, Amoeba dubia. This protozoan genome has 670 billion units of DNA, or base pairs. The genome of a cousin, Amoeba proteus, has a mere 290 billion base pairs, making it 100 times larger than the human genome.
The hepatitis C virus (HCV) is a small, enveloped, single-stranded positive sense RNA virus with a diameter of about 50 nm belonging to the Hepacivirus genus of the family Flaviviridae. The HCV genome is translated to produce a single protein of around 3011 amino acids.
DNA ميتوكندريايي داراي خواصي است كه مي تواند در تشخيص هويت مخصوصا در مواردي كه DNA هسته اي به مقدار كافي وجود ندارد مفيد باشد. از جمله اين ويژگي ها مي توان به تعداد زياد نسخه ها در سلول، مقاومت بيشتر در برابر تخريب و كوتاه بودن طول ژنوم اشاره كرد.